Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Päätekijät: Wataru Nemoto (Tekijä), Kotaro Yamada (Tekijä), Osamu Nakagawasai (Tekijä), Yoshiki Ogata (Tekijä), Masato Chiba (Tekijä), Ryota Yamagata (Tekijä), Hidetomo Sakurai (Tekijä), Koichi Tan-No (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2018-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...