Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Príomhchruthaitheoirí: Wataru Nemoto (Údar), Kotaro Yamada (Údar), Osamu Nakagawasai (Údar), Yoshiki Ogata (Údar), Masato Chiba (Údar), Ryota Yamagata (Údar), Hidetomo Sakurai (Údar), Koichi Tan-No (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2018-08-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...