Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• मुख्य लेखकों: Wataru Nemoto (लेखक), Kotaro Yamada (लेखक), Osamu Nakagawasai (लेखक), Yoshiki Ogata (लेखक), Masato Chiba (लेखक), Ryota Yamagata (लेखक), Hidetomo Sakurai (लेखक), Koichi Tan-No (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2018-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...