Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Үндсэн зохиолчид: Wataru Nemoto (Зохиогч), Kotaro Yamada (Зохиогч), Osamu Nakagawasai (Зохиогч), Yoshiki Ogata (Зохиогч), Masato Chiba (Зохиогч), Ryota Yamagata (Зохиогч), Hidetomo Sakurai (Зохиогч), Koichi Tan-No (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2018-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...