Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Главные авторы: Wataru Nemoto (Автор), Kotaro Yamada (Автор), Osamu Nakagawasai (Автор), Yoshiki Ogata (Автор), Masato Chiba (Автор), Ryota Yamagata (Автор), Hidetomo Sakurai (Автор), Koichi Tan-No (Автор)
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• Опубликовано: Elsevier, 2018-08-01T00:00:00Z.
• Предметы: article
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We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...