Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Asıl Yazarlar: Wataru Nemoto (Yazar), Kotaro Yamada (Yazar), Osamu Nakagawasai (Yazar), Yoshiki Ogata (Yazar), Masato Chiba (Yazar), Ryota Yamagata (Yazar), Hidetomo Sakurai (Yazar), Koichi Tan-No (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2018-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...