Knockdown lncRNA DLEU1 Inhibits Gliomas Progression and Promotes Temozolomide Chemosensitivity by Regulating Autophagy

• Main Authors: Qiao-Li Lv (Author), Li-Chong Wang (Author), Dang-Chi Li (Author), Qian-Xia Lin (Author), Xiao-Li Shen (Author), Hai-Yun Liu (Author), Min Li (Author), Yu-Long Ji (Author), Chong-Zhen Qin (Author), Shu-Hui Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gliomas are the most fatal malignant cerebral tumors. Temozolomide (TMZ), as the primary chemotherapy drug, has been widely used in clinics. However, resistance of TMZ still remains to poor defined. LncRNAs have been reported to play crucial roles in progression of various cancers and resistance of...