Bioconcentration and Metabolism of Emodin in Zebrafish Eleutheroembryos

• Main Authors: Jiefeng Chen (Author), Shaodong Li (Author), Mengping Liu (Author), Christopher Wai Kei Lam (Author), Zheng Li (Author), Xinjun Xu (Author), Zuanguang Chen (Author), Wei Zhang (Author), Meicun Yao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Emodin is a major active anthraquinone of various herbal laxatives, which can exert many pharmacological effects. However, chronic use of anthranoid laxatives, even at low dosages, may cause melanosis coli (MC). It has been suggested that the accumulation of anthraquinones is a risk factor in the MC...