Quercetin suppresses ROS production and migration by specifically targeting Rac1 activation in gliomas

• Main Authors: Rafia A. Baba (Author), Hilal A. Mir (Author), Taseem A. Mokhdomi (Author), Hina F. Bhat (Author), Ajaz Ahmad (Author), Firdous A. Khanday (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

P66Shc and Rac1 proteins are responsible for tumor-associated inflammation, particularly in brain tumors characterized by elevated oxidative stress and increased reactive oxygen species (ROS) production. Quercetin, a natural polyphenolic flavonoid, is a well-known redox modulator with anticancer pro...