Challenges, Solutions, and Quality Metrics of Personal Genome Assembly in Advancing Precision Medicine

• Main Authors: Wenming Xiao (Author), Leihong Wu (Author), Gokhan Yavas (Author), Vahan Simonyan (Author), Baitang Ning (Author), Huixiao Hong (Author)
• Format: Book
• Published: MDPI AG, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Even though each of us shares more than 99% of the DNA sequences in our genome, there are millions of sequence codes or structure in small regions that differ between individuals, giving us different characteristics of appearance or responsiveness to medical treatments. Currently, genetic variants i...