Hydrophobic Modification of Poly(γ-glutamic acid) by Grafting 4-Phenyl-butyl Side Groups for the Encapsulation and Release of Doxorubicin

• Main Authors: Porochista Dorost (Author), Montserrat García-Alvarez (Author), Antxon Martínez de Ilarduya (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The delivery of drugs is a great challenge, since most of active pharmaceutical ingredients developed today are hydrophobic and poorly water soluble. From this perspective, drug encapsulation on biodegradable and biocompatible polymers can surpass this problem. Poly(γ-glutamic acid) (PGGA), a bioedi...