A Macrophage Membrane-Polymer Hybrid Biomimetic Nanoplatform for Therapeutic Delivery of Somatostatin Peptide to Chronic Pancreatitis

• Main Authors: Fang Wang (Author), Yu Deng (Author), Luying Yu (Author), Ao Zhou (Author), Jieting Wang (Author), Jingyan Jia (Author), Ning Li (Author), Fadian Ding (Author), Wei Lian (Author), Qicai Liu (Author), Yu Yang (Author), Xinhua Lin (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The clinical translation of therapeutic peptides is generally challenged by multiple issues involving absorption, distribution, metabolism and excretion. In this study, a macrophage membrane-coated poly(lactic-co-glycolic acid) (PLGA) nanodelivery system was developed to enhance the bioavailability...