A Macrophage Membrane-Polymer Hybrid Biomimetic Nanoplatform for Therapeutic Delivery of Somatostatin Peptide to Chronic Pancreatitis

• 主要な著者: Fang Wang (著者), Yu Deng (著者), Luying Yu (著者), Ao Zhou (著者), Jieting Wang (著者), Jingyan Jia (著者), Ning Li (著者), Fadian Ding (著者), Wei Lian (著者), Qicai Liu (著者), Yu Yang (著者), Xinhua Lin (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The clinical translation of therapeutic peptides is generally challenged by multiple issues involving absorption, distribution, metabolism and excretion. In this study, a macrophage membrane-coated poly(lactic-co-glycolic acid) (PLGA) nanodelivery system was developed to enhance the bioavailability...