Caryophyllene Oxide Induces Ferritinophagy by Regulating the NCOA4/FTH1/LC3 Pathway in Hepatocellular Carcinoma

• Main Authors: Zhiru Xiu (Author), Yilong Zhu (Author), Jicheng Han (Author), Yaru Li (Author), Xia Yang (Author), Guohua Yang (Author), Gaojie Song (Author), Shanzhi Li (Author), Yue Li (Author), Cheng Cheng (Author), Yiquan Li (Author), Jinbo Fang (Author), Xiao Li (Author), Ningyi Jin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferritinophagy is associated with tumor occurrence, development, and therapy effects. Ferritinophagy and ferroptosis are regulated by iron metabolism and are closely connected. LC3 protein is a key protein in autophagy. Following the binding of NCOA4 to FTH1, it links to LC3Ⅱ in lysosomes, a symbol...