Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2

• Main Authors: Yanjie Cheng (Author), Zhuying Wei (Author), Shengsong Xie (Author), You Peng (Author), Yi Yan (Author), Dan Qin (Author), Shenghui Liu (Author), Yanling Xu (Author), Guangpeng Li (Author), Lisheng Zhang (Author)
• Format: Book
• Published: Elsevier, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Widely varied compounds, including certain plasticizers, hypolipidemic drugs (e.g., ciprofibrate, fenofibrate, WY-14643, and clofibrate), agrochemicals, and environmental pollutants, are peroxisome proliferators (PPs). Appropriate dose of PPs causes a moderate increase in the number and size of pero...