MHC Class I Stability is Modulated by Cell Surface Sialylation in Human Dendritic Cells

• Main Authors: Zélia Silva (Author), Tiago Ferro (Author), Danielle Almeida (Author), Helena Soares (Author), José Alexandre Ferreira (Author), Fanny M. Deschepper (Author), Paul J. Hensbergen (Author), Martina Pirro (Author), Sandra J. van Vliet (Author), Sebastian Springer (Author), Paula A. Videira (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Maturation of human Dendritic Cells (DCs) is characterized by increased expression of antigen presentation molecules, and overall decreased levels of sialic acid at cell surface. Here, we aimed to identify sialylated proteins at DC surface and comprehend their role and modulation. Mass spectrometry...