Nose-to-brain drug delivery by HS15 micelles for brain targeting of insoluble drug

• Κύριοι συγγραφείς: Wei Zhang (Συγγραφέας), Long Wan (Συγγραφέας), Meiqi Han (Συγγραφέας), Wen Guo (Συγγραφέας), Zhiqi Wang (Συγγραφέας), Xinyue Zhang (Συγγραφέας), Xuyang Liu (Συγγραφέας), Jiahao Wang (Συγγραφέας), Yuling Mao (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Compuscript Ltd, 2024-04-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Agomelatine (AGO) is an antidepressant with limited clinical application due to its low bioavailability caused by poor water solubility, severe hepatic degradation, and poor intracerebral distribution. Nanotechnology-based strategies constitute a powerful tool by utilizing drug solubility and target...