Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors

Cytotoxic substituted indolizines as new colchicine site tubulin polymerisation inhibitors

A potential microtubule destabilising series of new indolizine derivatives was synthesised and tested for their anticancer activity against a panel of 60 human cancer cell lines. Compounds 11a, 11b, 15a, and 15j showed a broad spectrum of growth inhibitory activity against cancer cell lines represen...

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Main Authors: Monica-Cornelia Sardaru (Author), Anda Mihaela Craciun (Author), Cristina-Maria Al Matarneh (Author), Isabela Andreea Sandu (Author), Roxana Maria Amarandi (Author), Lacramioara Popovici (Author), Catalina Ionica Ciobanu (Author), Dragos Peptanariu (Author), Mariana Pinteala (Author), Ionel I. Mangalagiu (Author), Ramona Danac (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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