Synergistic ultrasonic biophysical effect-responsive nanoparticles for enhanced gene delivery to ovarian cancer stem cells

• Main Authors: Chun Liufu (Author), Yue Li (Author), Yan Lin (Author), Jinsui Yu (Author), Meng Du (Author), Yuhao Chen (Author), Yaozhang Yang (Author), Xiaojing Gong (Author), Zhiyi Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ovarian cancer stem cells (OCSCs) that are a subpopulation within bulk tumor survive chemotherapy and conduce to chemo-resistance and tumor relapse. However, conventional gene delivery is unsuitable for the on-demand content release, which limits OCSCs therapeutic utility. Here, we reported ultrasou...