Imaging-Based Drug Penetration Profiling in an Excised Sheep Cornea Model

• Main Authors: Karla Viehmeister (Author), Aurélie Manuelli (Author), Camille Guerin (Author), Sebastian Kappes (Author), Alf Lamprecht (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Formulations designed to address ocular conditions and diseases are predominantly administered topically. While in vitro test systems have been developed to assess corneal permeation under extended contact conditions, methods focusing on determining the penetration depth and kinetics of a substance...