The Spliceosome Factor EFTUD2 Promotes IFN Anti-HBV Effect through mRNA Splicing

• Main Authors: Pingping Hu (Author), Yuwen Li (Author), Wen Zhang (Author), Rui Liu (Author), Linya Peng (Author), Ruirui Xu (Author), Jinyuan Cai (Author), Hui Yuan (Author), Tiantong Feng (Author), Anran Tian (Author), Ming Yue (Author), Jun Li (Author), Wenting Li (Author), Chuanlong Zhu (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims. The underlying mechanisms of differential responsiveness to IFN remain poorly understood. The elongation factor Tu GTP binding domain-containing protein 2 (EFTUD2), involved in RNA splicing and pre-mRNA processing, was recognized as a novel innate immune regulator of the IFN antihep...