Synthesis, Characterization and Host-Guest Complexation of Asplatin: Improved In Vitro Cytotoxicity and Biocompatibility as Compared to Cisplatin

• Main Authors: Sherif Ashraf Fahmy (Author), Fortuna Ponte (Author), Giulia Grande (Author), Iten M. Fawzy (Author), Asmaa A. Mandour (Author), Emilia Sicilia (Author), Hassan Mohamed El-Said Azzazy (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Para-</i>sulfocalix[n]arenes are promising host molecules that can accommodate various chemotherapeutic drugs. Pt(IV)-based complexes, including satraplatin and asplatin, are promising alternatives that overcome the shortcomings of Pt(II) complexes. In this study, asplatin has been sy...