Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of <i>Schistosoma mansoni</i> Infection

• প্রধান লেখক: Omary Mashiku Minzi (লেখক), Rajabu Hussein Mnkugwe (লেখক), Eliford Ngaimisi (লেখক), Safari Kinung'hi (লেখক), Anna Hansson (লেখক), Anton Pohanka (লেখক), Appolinary Kamuhabwa (লেখক), Eleni Aklillu (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2021-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Praziquantel (PZQ) and dihydroartemisinin-piperaquine (DHP) combination recently showed superior effectiveness than PZQ alone to treat intestinal schistosomiasis. In this follow-up study, we investigated the effect of DHP co-administration on the pharmacokinetics of PZQ and its enantiomers among 64...