Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of <i>Schistosoma mansoni</i> Infection

• Asıl Yazarlar: Omary Mashiku Minzi (Yazar), Rajabu Hussein Mnkugwe (Yazar), Eliford Ngaimisi (Yazar), Safari Kinung'hi (Yazar), Anna Hansson (Yazar), Anton Pohanka (Yazar), Appolinary Kamuhabwa (Yazar), Eleni Aklillu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Praziquantel (PZQ) and dihydroartemisinin-piperaquine (DHP) combination recently showed superior effectiveness than PZQ alone to treat intestinal schistosomiasis. In this follow-up study, we investigated the effect of DHP co-administration on the pharmacokinetics of PZQ and its enantiomers among 64...