Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of <i>Schistosoma mansoni</i> Infection

• Główni autorzy: Omary Mashiku Minzi (Autor), Rajabu Hussein Mnkugwe (Autor), Eliford Ngaimisi (Autor), Safari Kinung'hi (Autor), Anna Hansson (Autor), Anton Pohanka (Autor), Appolinary Kamuhabwa (Autor), Eleni Aklillu (Autor)
• Format: Książka
• Wydane: MDPI AG, 2021-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Praziquantel (PZQ) and dihydroartemisinin-piperaquine (DHP) combination recently showed superior effectiveness than PZQ alone to treat intestinal schistosomiasis. In this follow-up study, we investigated the effect of DHP co-administration on the pharmacokinetics of PZQ and its enantiomers among 64...