Characterization, Stability, and In Vivo Efficacy Studies of Recombinant Human CNTF and Its Permeation into the Neural Retina in Ex Vivo Organotypic Retinal Explant Culture Models

• Главные авторы: Jaakko Itkonen (Автор), Ada Annala (Автор), Shirin Tavakoli (Автор), Blanca Arango-Gonzalez (Автор), Marius Ueffing (Автор), Elisa Toropainen (Автор), Marika Ruponen (Автор), Marco G. Casteleijn (Автор), Arto Urtti (Автор)
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• Опубликовано: MDPI AG, 2020-06-01T00:00:00Z.
• Предметы: article
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Ciliary neurotrophic factor (CNTF) is one of the most studied neuroprotective agents with acknowledged potential in treating diseases of the posterior eye segment. Although its efficacy and mechanisms of action in the retina have been studied extensively, it is still not comprehensively understood w...