Asymmetric Synthesis of US-FDA Approved Drugs over Five Years (2016-2020): A Recapitulation of Chirality

• Ngā kaituhi matua: Rekha Tamatam (Author), Dongyun Shin (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2023-02-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Chirality is a major theme in the design, discovery, and development of new drugs. Historically, pharmaceuticals have been synthesized as racemic mixtures. However, the enantiomeric forms of drug molecules have distinct biological properties. One enantiomer may be responsible for the desired therape...