Tissue distribution and integrated pharmacokinetic properties of major effective constituents of oral Gegen-Qinlian decoction in mice

• Main Authors: Jing-Ze Lu (Author), Dan-Dan Hong (Author), Dan Ye (Author), Sheng Mu (Author), Rong Shi (Author), Yu Song (Author), Chu Feng (Author), Bing-Liang Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gegen-Qinlian decoction (GQD) is a classic traditional Chinese medicine (TCM) formula. GQD is effective against colon or liver-related diseases including ulcerative colitis, non-alcoholic fatty liver, and type 2 diabetes. In this study, a liquid chromatography-tandem mass spectrometry method was dev...