Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test

• Main Authors: Madeleine Wallenius (Author), Alexander Lind (Author), Omar Akel (Author), Emma Karlsson (Author), Markus Svensson (Author), Elin Arvidsson (Author), Anita Ramelius (Author), Carina Törn (Author), Lars Palm (Author), Åke Lernmark (Author), Helena Elding Larsson (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Study objectives: Narcolepsy type 1 (NT1) is a chronic sleep disorder characterized by loss of hypocretin-producing neurons. Increased NT1 incidence was observed in Sweden following mass-vaccination with Pandemrix®. Genetic association to HLA DQB1*06:02 implies an autoimmune origin, but target autoa...