Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis

• Main Authors: Victoria Chapman (Author), Hareklea Markides (Author), Devi Rani Sagar (Author), Luting Xu (Author), James J. Burston (Author), Paul Mapp (Author), Alasdair Kay (Author), Robert H. Morris (Author), Oksana Kehoe (Author), Alicia J. El Haj (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Mesenchymal stem cells (MSCs) have a therapeutic potential for the treatment of osteoarthritic (OA) joint pathology and pain. The aims of this study were to determine the influence of a passage number on the effects of MSCs on pain behaviour and cartilage and bone features in a rodent mo...