Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes
Objective: Aging and weight gain lead to a decline in brown and beige adipocyte functionality that exacerbates obesity and insulin resistance. We sought to determine whether sphingolipids, such as ceramides, a class of lipid metabolites that accumulate in aging and overnutrition, are sufficient or n...
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Elsevier,
2021-03-01T00:00:00Z.
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