Global Metabolomics Reveals the Metabolic Dysfunction in Ox-LDL Induced Macrophage-Derived Foam Cells

• Main Authors: Wenjuan Xu (Author), Ziyi Wei (Author), Jiaojiao Dong (Author), Feipeng Duan (Author), Kuikui Chen (Author), Chang Chen (Author), Jie Liu (Author), Xiaowei Yang (Author), Lianming Chen (Author), Hongbin Xiao (Author), An Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atherosclerosis (AS) is a chronic disorder of large arteries that is a major risk factors of high morbidity and mortality. Oxidative modification LDL is one of the important contributors to atherogenesis. Macrophages take up ox-LDL and convert into foam cells, which is the hallmark of AS. To advance...