Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin

• Main Authors: Gonzalo Villapalos-García (Author), Pablo Zubiaur (Author), Marcos Navares-Gómez (Author), Miriam Saiz-Rodríguez (Author), Gina Mejía-Abril (Author), Samuel Martín-Vílchez (Author), Manuel Román (Author), Dolores Ochoa (Author), Francisco Abad-Santos (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dutasteride and tamsulosin are one of the first-line combination therapies for the management of benign prostatic hyperplasia (BPH). Despite being more effective than monotherapies, they produce frequent adverse drug reactions (ADRs). Institutions such as Food and Drug Administration and European Me...