Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases

• Hoofdauteurs: Mikhail Krasavin (Auteur), Mikhail Korsakov (Auteur), Oksana Ronzhina (Auteur), Tiziano Tuccinardi (Auteur), Stanislav Kalinin (Auteur), Muhammet Tanç (Auteur), Claudiu T. Supuran (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

A diverse set of mono- and bis-sulfonamide was obtained via a direct, chemoselective sulfochlorination of readily available yet hitherto unexplored N-arylpyrazole template. Biochemical profiling of compounds thus obtained against a panel of human carbonic anhydrases (hCA I, hCA II, hCA IV and hCA VI...