Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases

Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases

A diverse set of mono- and bis-sulfonamide was obtained via a direct, chemoselective sulfochlorination of readily available yet hitherto unexplored N-arylpyrazole template. Biochemical profiling of compounds thus obtained against a panel of human carbonic anhydrases (hCA I, hCA II, hCA IV and hCA VI...

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Main Authors: Mikhail Krasavin (Author), Mikhail Korsakov (Author), Oksana Ronzhina (Author), Tiziano Tuccinardi (Author), Stanislav Kalinin (Author), Muhammet Tanç (Author), Claudiu T. Supuran (Author)
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Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
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