Supplementation of Saponins from Leaves of <i>Panax quinquefolius</i> Mitigates Cisplatin-Evoked Cardiotoxicity via Inhibiting Oxidative Stress-Associated Inflammation and Apoptosis in Mice

• Main Authors: Jing-Jing Xing (Author), Jin-Gang Hou (Author), Ying Liu (Author), Ruo-Bing Zhang (Author), Shuang Jiang (Author), Shen Ren (Author), Ying-Ping Wang (Author), Qiong Shen (Author), Wei Li (Author), Xin-Dian Li (Author), Zi Wang (Author)
• Format: Book
• Published: MDPI AG, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Although kidney injury caused by cisplatin has attracted much attention, cisplatin-induced cardiotoxicity is elusive. Our previous studies have confirmed that saponins (ginsenosides) from <i>Panax quinquefolius</i> can effectively reduce acute renal injuries. Our current stud...