Multifactorial Modes of Action of Arsenic Trioxide in Cancer Cells as Analyzed by Classical and Network Pharmacology

Arsenic trioxide is a traditional remedy in Chinese Medicine since ages. Nowadays, it is clinically used to treat acute promyelocytic leukemia (APL) by targeting PML/RARA. However, the drug's activity is broader and the mechanisms of action in other tumor types remain unclear. In this study, we...

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Hoofdauteurs: Mona Dawood (Auteur), Sami Hamdoun (Auteur), Thomas Efferth (Auteur)
Formaat: Boek
Gepubliceerd in: Frontiers Media S.A., 2018-02-01T00:00:00Z.
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