Novel 1-Amidino-4-Phenylpiperazines as Potent Agonists at Human TAAR1 Receptor: Rational Design, Synthesis, Biological Evaluation and Molecular Docking Studies

• Glavni autori: Valeria Francesconi (Autor), Elena Cichero (Autor), Evgeny V. Kanov (Autor), Erik Laurini (Autor), Sabrina Pricl (Autor), Raul R. Gainetdinov (Autor), Michele Tonelli (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2020-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Targeting trace amine-associated receptor 1 (TAAR1) receptor continues to offer an intriguing opportunity to develop innovative therapies in different pharmacological settings. Pursuing our endeavors in the search for effective and safe human TAAR1 (<i>h</i>TAAR1) ligands, we synthesized...