Novel 1-Amidino-4-Phenylpiperazines as Potent Agonists at Human TAAR1 Receptor: Rational Design, Synthesis, Biological Evaluation and Molecular Docking Studies

• Main Authors: Valeria Francesconi (Author), Elena Cichero (Author), Evgeny V. Kanov (Author), Erik Laurini (Author), Sabrina Pricl (Author), Raul R. Gainetdinov (Author), Michele Tonelli (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeting trace amine-associated receptor 1 (TAAR1) receptor continues to offer an intriguing opportunity to develop innovative therapies in different pharmacological settings. Pursuing our endeavors in the search for effective and safe human TAAR1 (<i>h</i>TAAR1) ligands, we synthesized...