Identification and Characterization of Novel CFTR Potentiators

• Главные авторы: Maarten Gees (Автор), Sara Musch (Автор), Steven Van der Plas (Автор), Anne-Sophie Wesse (Автор), Ann Vandevelde (Автор), Katleen Verdonck (Автор), Oscar Mammoliti (Автор), Tzyh-Chang Hwang (Автор), Kathleen Sonck (Автор), Pieter Stouten (Автор), Andrew M. Swensen (Автор), Mia Jans (Автор), Jan Van der Schueren (Автор), Luc Nelles (Автор), Martin Andrews (Автор), Katja Conrath (Автор)
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• Опубликовано: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

There is still a high unmet need for the treatment of most patients with cystic fibrosis (CF). The identification and development of new Cystic Fibrosis Transmembrane conductance Regulator (CFTR) modulators is necessary to achieve higher clinical benefit in patients. In this report we describe the c...