Prediction of Drug-Drug-Gene Interaction Scenarios of (<i>E</i>)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling
Clomiphene, a selective estrogen receptor modulator (SERM), has been used for the treatment of anovulation for more than 50 years. However, since (<i>E</i>)-clomiphene ((<i>E</i>)-Clom) and its metabolites are eliminated primarily via Cytochrome P450 (CYP) 2D6 and CYP3A4, exp...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2022-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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