Suppressive activity of RGX-365 on HMGB1-mediated septic responses

• Main Authors: Wonhwa Lee (Author), Ji-Eun Kim (Author), Sumin Yang (Author), Bong-Seon Lee (Author), Soo-Hyun Cho (Author), Jee-Hyun Lee (Author), Ga-Eun Choi (Author), Eui Kyun Park (Author), Gyu-Yong Song (Author), Jong-Sup Bae (Author)
• Format: Book
• Published: Universidade de São Paulo, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract RGX-365 is the main fraction of black ginseng conmprising protopanaxatriol (PPT)-type rare ginsenosides (ginsenosides Rg4, Rg6, Rh4, Rh1, and Rg2). No studies on the antiseptic activity of RGX-365 have been reported. High mobility group box 1 (HMGB1) is recognized as a late mediator of seps...