Fhl5/Act, a CREM-binding transcriptional activator required for normal sperm maturation and morphology, is not essential for testicular gene expression

• Main Authors: Kotaja Noora (Author), Demougin Philippe (Author), Chalmel Frédéric (Author), Lardenois Aurélie (Author), Sassone-Corsi Paolo (Author), Primig Michael (Author)
• Format: Book
• Published: BMC, 2009-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The LIM domain protein Fhl5 was previously found to interact with CREM, a DNA binding transcriptional regulator necessary for spermiogenesis in mammals. Co-transfection experiments using heterologous promoter constructs indicated a r...