Fhl5/Act, a CREM-binding transcriptional activator required for normal sperm maturation and morphology, is not essential for testicular gene expression

• Autori principali: Kotaja Noora (Autore), Demougin Philippe (Autore), Chalmel Frédéric (Autore), Lardenois Aurélie (Autore), Sassone-Corsi Paolo (Autore), Primig Michael (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2009-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The LIM domain protein Fhl5 was previously found to interact with CREM, a DNA binding transcriptional regulator necessary for spermiogenesis in mammals. Co-transfection experiments using heterologous promoter constructs indicated a r...