Polyphyllin I alleviates neuroinflammation after cerebral ischemia-reperfusion injury via facilitating autophagy-mediated M2 microglial polarization

• मुख्य लेखकों: Chunyang Kang (लेखक), Qiuling Sang (लेखक), Dingxi Liu (लेखक), Libo Wang (लेखक), Jia Li (लेखक), Xiaoyang Liu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Microglial activation and polarization play a central role in poststroke inflammation and neuronal damage. Modulating microglial polarization from pro-inflammatory to anti-inflammatory phenotype is a promising therapeutic strategy for the treatment of cerebral ischemia. Polyphyllin I (PPI),...