Polyphyllin I alleviates neuroinflammation after cerebral ischemia-reperfusion injury via facilitating autophagy-mediated M2 microglial polarization

Abstract Microglial activation and polarization play a central role in poststroke inflammation and neuronal damage. Modulating microglial polarization from pro-inflammatory to anti-inflammatory phenotype is a promising therapeutic strategy for the treatment of cerebral ischemia. Polyphyllin I (PPI),...

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Main Authors: Chunyang Kang (Author), Qiuling Sang (Author), Dingxi Liu (Author), Libo Wang (Author), Jia Li (Author), Xiaoyang Liu (Author)
Format: Book
Published: BMC, 2024-05-01T00:00:00Z.
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