Piperazine ferulate inhibits diabetic nephropathy by suppressing AGE/RAGE-mediated inflammatory signaling in rats and podocytes

• Main Authors: Xiu-Meng Zhang (Author), Xin-Ran Min (Author), Hong-Xiao Xie (Author), Yan-Ning Jiang (Author), Yi-Xin Rui (Author), Bo Li (Author), Nan Zeng (Author), Rong Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Diabetic nephropathy (DN) is a serious complication that may occur during the later stages of diabetes, and can be further exacerbated by podocyte damage. Piperazine ferulate (PF) has well-defined nephroprotective effects and is used clinically in the treatment of chronic nephritis and ot...