2,4,6-Trihydroxy-3-geranyl acetophenone suppresses vascular leakage and leukocyte infiltration in lipopolysaccharide-induced endotoxemic mice

• Main Authors: Yee Han Chan (Author), Nazmi Firdaus Musa (Author), Yi Joong Chong (Author), Siti Arfah Saat (Author), Faizul Hafiz (Author), Khozirah Shaari (Author), Daud Ahmad Israf (Author), Chau Ling Tham (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Lipopolysaccharide (LPS) exacerbates systemic inflammatory responses and causes excessive fluid leakage. 2,4,6-Trihydroxy-3-geranyl acetophenone (tHGA) has been revealed to protect against LPS-induced vascular inflammation and endothelial hyperpermeability in vitro. Objective This study asse...