Pharmacokinetic‐pharmacodynamic model of urinary δ‐aminolevulinic acid reduction after givosiran treatment in patients with acute hepatic porphyria
Abstract Givosiran, an RNA interference‐based therapeutic, is a recent addition to the limited treatment armamentarium for acute hepatic porphyria (AHP). As a small interfering RNA that is selectively taken up in the liver, both the mechanism and targeted delivery create a complex relationship betwe...
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Formato: | Libro |
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Wiley,
2023-06-01T00:00:00Z.
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Acceso en línea: | Connect to this object online. |
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Número de Clasificación: |
A1234.567 |
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