Diagnostic challenges posed by a rare alpha globin chain variant Hb Fontainebleau in a pregnant female and its potential effects in her children in view of multiple globin gene defects in her husband

• Main Authors: Kainaz Sidhwa (Author), Manisha Ramani Daruwalla (Author), Ravikiran Pawar (Author), Anita Nadkarni (Author), Priya Hariharan (Author), Pallavi Mehta (Author), Amar Das Gupta (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alpha globin chain variants per se do not cause severe morbidity and mortality but can modify - usually ameliorate - the clinical manifestations of beta globin chain variants when co-inherited with the latter. They also pose challenges in interpretation of high-performance liquid chromatography hist...