AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

• Main Authors: Iain R. Phair (Author), Raid B. Nisr (Author), Andrew J.M. Howden (Author), Magdalena Sovakova (Author), Noor Alqurashi (Author), Marc Foretz (Author), Douglas Lamont (Author), Benoit Viollet (Author), Graham Rena (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Previous mechanistic studies on immunometabolism have focused on metabolite-based paradigms of regulation, such as itaconate. Here, we, demonstrate integration of metabolite and kinase-based immunometabolic control by AMP kinase. Methods: We combined whole cell quantitative proteomics wit...