AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

• मुख्य लेखकों: Iain R. Phair (लेखक), Raid B. Nisr (लेखक), Andrew J.M. Howden (लेखक), Magdalena Sovakova (लेखक), Noor Alqurashi (लेखक), Marc Foretz (लेखक), Douglas Lamont (लेखक), Benoit Viollet (लेखक), Graham Rena (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Previous mechanistic studies on immunometabolism have focused on metabolite-based paradigms of regulation, such as itaconate. Here, we, demonstrate integration of metabolite and kinase-based immunometabolic control by AMP kinase. Methods: We combined whole cell quantitative proteomics wit...