AMPK integrates metabolite and kinase-based immunometabolic control in macrophages

• Príomhchruthaitheoirí: Iain R. Phair (Údar), Raid B. Nisr (Údar), Andrew J.M. Howden (Údar), Magdalena Sovakova (Údar), Noor Alqurashi (Údar), Marc Foretz (Údar), Douglas Lamont (Údar), Benoit Viollet (Údar), Graham Rena (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2023-02-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Objective: Previous mechanistic studies on immunometabolism have focused on metabolite-based paradigms of regulation, such as itaconate. Here, we, demonstrate integration of metabolite and kinase-based immunometabolic control by AMP kinase. Methods: We combined whole cell quantitative proteomics wit...