Highly Potent GalNAc-Conjugated Tiny LNA Anti-miRNA-122 Antisense Oligonucleotides

Highly Potent GalNAc-Conjugated Tiny LNA Anti-miRNA-122 Antisense Oligonucleotides

The development of clinically relevant anti-microRNA antisense oligonucleotides (anti-miRNA ASOs) remains a major challenge. One promising configuration of anti-miRNA ASOs called "tiny LNA (tiny Locked Nucleic Acid)" is an unusually small (~8-mer), highly chemically modified anti-miRNA ASO...

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Main Authors: Tsuyoshi Yamamoto (Author), Yahiro Mukai (Author), Fumito Wada (Author), Chisato Terada (Author), Yukina Kayaba (Author), Kaho Oh (Author), Asako Yamayoshi (Author), Satoshi Obika (Author), Mariko Harada-Shiba (Author)
Format: Book
Published: MDPI AG, 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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