Altered Viral Replication and Cell Responses by Inserting MicroRNA Recognition Element into PB1 in Pandemic Influenza A Virus (H1N1) 2009

Objective. MicroRNAs (miRNAs) are endogenous noncoding RNAs that spatiotemporally modulate mRNAs in a posttranscriptional manner. Engineering mutant viruses by inserting cell-specific miRNA recognition element (MRE) into viral genome may alter viral infectivity and host responses in vital tissues an...

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Main Authors: Xiaoyue Shen (Author), Wenkui Sun (Author), Yi Shi (Author), Zheng Xing (Author), Xin Su (Author)
Format: Book
Published: Hindawi Limited, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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