Identification of potential causal variants for premature ovarian failure by whole exome sequencing

• Main Authors: Haengun Jin (Author), JuWon Ahn (Author), YoungJoon Park (Author), JeongMin Sim (Author), Han Sung Park (Author), Chang Soo Ryu (Author), Nam Keun Kim (Author), KyuBum Kwack (Author)
• Format: Book
• Published: BMC, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Premature ovarian failure (POF) is a highly heterogeneous disorder that occurs in 1% of women of reproductive age. Very few causative genes and variants contributing to POF have been detected, and the disease remains incompletely understood. In this study, we used whole exome seq...