Design of experiments assisted the development of inclusion complexes of ramipril using hydrophilic carriers for enhancement of solubility and dissolution rate

• Principais autores: Azeez Mohammad (Autor), Sumer Singh (Autor), Suryakanta Swain (Autor), Rabinarayan Parhi (Autor)
• Formato: Livro
• Publicado em: Universidade de São Paulo, 2023-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract The goal of the present study was to develop inclusion complexes and polymers dispersions of ramipril prepared by physical mixing, kneading, co-evaporation, and solvent evaporation methods to enhance drug solubility and dissolution rate, and thereby to reduce drug dose and side effects usin...