Prometastatic CXCR4 and Histone Methyltransferase EZH2 Are Upregulated in <em>SMARCB1</em>/<em>INI1</em>-Deficient and <em>TP53</em>-Mutated Poorly Differentiated Chordoma
Background: Chordoma is a rare tumor most commonly arising in the sacrococcygeal region from notochord remnants. Usually, these tumors are locally invasive and recurrent, and they have a 5-43% ability to metastasize. A newly-described aggressive variant called poorly differentiated chordoma is diffe...
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MDPI AG,
2022-04-01T00:00:00Z.
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