Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells

• Hoofdauteurs: Onat Kadioglu (Auteur), Betty Y. K. Law (Auteur), Simon W. F. Mok (Auteur), Su-Wei Xu (Auteur), Thomas Efferth (Auteur), Vincent K. W. Wong (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Neferine, a bisbenzylisoquinoline alkaloid isolated from the green seed embryos of Lotus (Nelumbo nucifera Gaertn), has been previously shown to have various anti-cancer effects. In the present study, we evaluated the effect of neferine in terms of P-glycoprotein (P-gp) inhibition via in vitro cytot...